From Route 93 North or Route 93 South
Take Route 93 North or South to exit 48 (MA-213 toward Methuen/Haverhill). Turn onto exit 2, Route 28 South (Methuen/Lawrence). Continue on Route 28 South for 1.4 miles. Take a left at the traffic light onto Daisy Street. Take your first right onto Holly Street and then take your first left onto the CCHS Campus.

From Route 495 North or Route 495 South
Follow Route 495 to the South Lawrence Route 114 exit. Follow sign for 114 West - Lawrence. This becomes Winthrop Avenue. Stay on Winthrop Avenue for about 1 mile until you cross the bridge over the Merrimack River. At the end of the bridge, turn left onto Canal Street. Take your first right onto Hampshire Street. Go through five sets of traffic lights and you will see the Central Catholic campus four blocks ahead on the left (after the last traffic light).